Unexplained infertility is one of the most common diagnoses in a fertility clinic with the prevalence of 15–30%
In fertile women uterine spiral artery perfusion has been found to improve during the luteal phase, which coincides with the implantation window.
Endometrial receptivity is regulated by many factors including uterine perfusion
Several studies have shown that uterine receptivity is decreased when the uterine artery impedance has been increased during the mid luteal phase.
Abnormal uterine perfusion may be a contributing factor to etiopathology of infertility especially in couples with unexplained infertility.
Transvaginal Doppler pulsed ultrasound is an important tool for examining the female reproductive system and is a non-invasive method to assess the uterine perfusion ( Uterine Blood flow )